A growing number of private companies are offering prospective parents using in-vitro fertilization polygenic screening of embryos to identify the risks for developing complex diseases later in life. Children have already been born from IVF cycles that integrated this screening. The use of polygenic risk reports for children and adults in clinical care raises unique questions about parental reproductive freedom as well as the forces and societal values that mobilize this practice. What is the validity of polygenic screening? Should polygenic screening of embryos become a standard offering as part of IVF, alongside currently common screens for aneuploidies? What are the risks? How should the conditions for which polygenic screening of embryos are offered be determined, and by what criteria? This ELSI Friday Forum explores the ELSI challenges of polygenic screening of embryos and stakeholders’ perspectives on this emerging practice. We will discuss its risks, limitations, and potential benefits for families and society at large.
Please visit the event webpage for speaker information.
Free and open to the public; registration required. For more information, please visit the event webpage.
Hosted by the Center for ELSI Resources and Analysis at Columbia University as part of the ELSI Friday Forum series.